A new and highly mutated strain of COVID-19 has been detected in at least ten states, but for now, the strain is rare, accounting for just a small fraction of new COVID cases nationwide. Dr. Bob Lahita, director of the Institute for Autoimmune and Rheumatic Diseases at Saint Joseph Health in Saddle River, New Jersey, joined CBS News to discuss the new variant. Source

The United Nations General Assembly begins Tuesday with President Biden and Ukrainian President Volodymyr Zelenskyy scheduled to address the annual gathering of world leaders. CBS News’ Jarred Hill is outside the U.N. with more on what we can expect. Source

Five Americans who were freed from Iran returned to the U.S. early Tuesday. The months-long prisoner swap negotiations ended with President Biden granting clemency to five Iranians in the U.S. and freeing up $6 billion in frozen funds for Iran. “Face the Nation” moderator and CBS News chief foreign affairs correspondent Margaret Brennan reports from Washington. Source

Clorox is slowly restoring its systems after a hack last month forced the consumer products maker to take them offline. Source

Two Massachusetts mothers — inspired by Nikki Puzzo’s daughter, Stella — hope to make adaptive clothing for people with disabilities mainstream through their brand, befree. Source

Senior Writer and Editor Jim Wyatt tackles another batch of questions from Titans fans in this Tuesday’s mailbag. Source

Complete broadcast information for this week’s game between the Tennessee Titans and the Cleveland Browns Source

Kickoff is scheduled for 1 p.m. EDT/noon CDT on Sunday, Sept. 24. Source

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New crash tests from the Insurance Institute for Highway Safety (IIHS) show the backseat of minivans may be unsafe for children. CBS News’ Kris Van Cleave shows you those tests and why the IIHS says changes must be made. Source