The collision at the Rainbow Bridge, a U.S.-Canada border crossing near Niagara Falls, left two people inside the vehicle dead, law enforcement sources confirmed to CBS News. Source

Injuries for the Titans Week 12 matchup against the Carolina Panthers Source

Sources say two people were killed in a vehicle explosion Wednesday afternoon at Rainbow Bridge, a U.S.-Canada border crossing near Niagara Falls. Kerry Schmidt, a sergeant with the Ontario Provincial Police Highway Safety Division, joins CBS News with updates on what drivers at the border need to know. Source

Iowa evangelical leader Bob Vander Plaats endorsed Florida Gov. Ron DeSantis for president. CBS News congressional correspondent Scott MacFarlane is looking into the new endorsement, and what could be next for Rep. George Santos. Source

The assassination of John F. Kennedy, the 35th president of the U.S., occurred 60 years ago Wednesday. Douglas Brinkley, a history professor and humanities chair at Rice University, joins CBS News to discuss how Kennedy’s assassination moved the nation. Source

Law enforcement sources confirmed to CBS News that two people died in the vehicle explosion at Rainbow Bridge, a border crossing between the U.S. and Canada near Niagara Falls, in western New York. Source

50 hostages held by Hamas and 150 Palestinian women and children held in Israeli prisons are set to be released after a deal was agreed to by the two sides. CBS News correspondent Lilia Luciano reports from Tel Aviv and chief foreign affairs correspondent and “Face the Nation” moderator Margaret Brennan gives analysis on the deal. Source

Israeli Prime Minister Benjamin Netanyahu addressed the Jewish state Wednesday to praise the Israel Defense Forces and other groups involved in the continued operations of the Israel-Hamas war. Netanyahu also said the war will continue after the temporary cease-fire Israel agreed to as part of a hostage deal with Hamas. Source

Federal regulators say early termination fees often prevent American consumers from choosing the TV service they want. Source

A respiratory illness in dogs that does not appear to respond to antibiotics is being investigated in several states across the U.S. Symptoms of the illness include coughing, sneezing, nasal or eye discharge and lethargy. Dr. David Needle, the pathology section chief at the New Hampshire Veterinary Diagnostic Lab, joins CBS News with details on the illness that could rapidly develop into pneumonia in some cases. Source