At least 16 people were killed in a shooting in Lewiston, Maine, Wednesday night, multiple law enforcement officials told CBS News, but they indicated the death toll could be higher than 20. Source

The United Auto Workers and Ford reached a tentative contract agreement Wednesday evening, a move that will be critical to ending the union’s six-week-old strikes against Detroit’s Big Three automakers. CBS News senior transportation correspondent Kris Van Cleave has more. Source

Jericka Duncan reports on the newly-elected House Speaker Mike Johnson, Gaza hospitals running out of fuel, and how climate change is linked to the rapid intensification of storms like Hurricane Otis. Source

Authorities responded to an active shooter at multiple locations in Lewiston, Maine State Police said. Source

The leader of a Mexican megachurch who is serving more than 16 years in a California prison for sexually abusing young followers has been charged with two federal crimes involving a 16-year-old girl. Source

Two Russian cosmonauts left the International Space Station for an hours-long spacewalk Wednesday to locate the source of a radiator coolant leak. CBS News space consultant Bill Harwood has the details. Source

With the tentative deal reached with Ford, the UAW will now be able to use it to model similar contract settlements with GM and Stellantis. Source

In under 24 hours, Tropical Storm Otis exploded in strength and hit Mexico as a Category 5 hurricane Wednesday. A new U.N. climate report issued the same day warns Earth is close to multiple “risk tipping points.” CBS News senior national and environmental correspondent Ben Tracy explains how it’s all connected. Source

World leaders are condemning the worsening humanitarian crisis in Gaza and are calling for an immediate ceasefire in the war. Jon Alterman, senior vice president and director of the Middle East program at the Center for Strategic and International Studies, joins CBS News to discuss the role President Biden could play in delaying a ground invasion. Source

As tensions rise across the U.S., so are incidents of antisemitism and Islamophobia, according to the Anti-Defamation League and Council on American Islamic Relations. CBS News chief national affairs and justice correspondent Jeff Pegues has more. Source