“We are in a very disastrous situation,” the governor said as the state is grappling with a surge of COVID-19 cases and hospitalizations. Source

President-elect Biden is starting to name his choices for Cabinet and national security positions. CBSN political reporter Caitlin Huey-Burns and Politico White House reporter Meridith McGraw spoke to “Red and Blue” host Elaine Quijano about what we’ve learned so far about the incoming administration. Source

With millions of people already on the road or in the air traveling for Thanksgiving, experts say it is guaranteed that cases of coronavirus will soon explode even more than they are right now. Source

The coronavirus vaccine being developed by AstraZeneca and the University of Oxford is up to 90% effective in preventing the disease, with clinical trials also showing that it may stop transmission among people. Charlie D’Agata continues our series “Racing to a Cure.” Source

A smartphone mixup brought two strangers together for a holiday feast in 2016, and a remarkable friendship developed. This Thanksgiving, they’re leaning on each other more than ever. Jamie Yuccas shares their story. Source

President-elect Joe Biden is signaling a dramatic shift in U.S. policy abroad, naming his picks for senior posts on his national security and foreign policy teams. Nikole Killion reports. Source

CBS News got rare access inside Jackson Memorial Hospital in Miami that will be among the first to receive Pfizer’s coronavirus vaccine. Mireya Villarreal shows us how health care workers are preparing for its distribution. Source

Former “Jeopardy!” contestant Ken Jennings will serve as the first of multiple interim hosts of the show following Alex Trebek’s death. Source

More than 1 million passengers boarded flights on Sunday despite CDC pleas to stay put. Expect full planes, experts say. Source

The air bags, which can explode and spew shrapnel under high-heat conditions, have killed 27 people worldwide. Source