As an actor playing a CIA director, Mandy Patinkin, narrator for the documentary, “The Spymasters: CIA in the Crosshairs,” reflects on the real-life CIA spymasters. For more, watch Saturday, May 21, at 9-11 p.m. ET/PT on CBS. | Complete coverage Source

Actor Mandy Patinkin, who plays the character Saul Berenson, CIA director and now CIA European division chief on the series “Homeland,” narrates the documentary “48 Hours Presents: The Spymasters: CIA in the Crosshairs” and compares the real CIA to the fictionalized version on TV. For more, watch Saturday, May 21, 9-11 p.m. ET/PT on CBS. | Complete coverage Source

Michael Weatherly has been playing special agent Tony DiNozzo on “NCIS” ever since the No.1 drama in the world premiered 13 seasons ago in 2003. But more than 300 episodes later, Weatherly will appear for one last time in Tuesday’s season finale. Weatherly joins “CBS This Morning” to discuss how he has come “full circle” and next steps in his career. Source

Sinead O’Connor has been reported missing after last being seen early leaving for a bike ride in a Chicago suburb on Sunday. Police say the singer was reported to be at risk of suicide. CBSN’s Vladimir Duthiers has the latest details. Source

Donald Trump is lashing out at the New York Times after the newspaper published personal stories from women who either met or knew the presumptive Republican nominee for president; with 46 years at “60 Minutes,” Morley Safer is the show’s longest-serving correspondent Source

60 Minutes’ longest-serving correspondent, who retired this week, talks about his early days at the broadcast and his famous rivalry with Mike Wallace Source

Correspondent Morley Safer likes to laugh, and America laughed with him when he interviewed the Muppets’ femme fatale, Miss Piggy. Take a look back at this and other funny Morley moments from Safer’s 46 seasons on 60 Minutes Source

How do you condense a 52-year CBS News career – including 919 stories for 60 Minutes – into an hour-long tribute? Three producers discuss the challenge Source

Scott Pelley continues his report on the Duke clinical trail of a new cancer therapy. Discoveries take Duke researchers in a direction they never imagined. Source

After more than 40 years, Garrison Keillor is departing from his endearing radio show, “A Prairie Home Companion.” His expert sound FX man, Fred Newman, thinks the void may be filled with a tale of Brooklyn baristas, and acts accordingly. Source